The phenomenon of gluten sensitivity in the absence of celiac disease is not new; it was first described in medical literature in the late 1970s. Since then, clinicians have continued to encounter patients who report adverse reactions to gluten, despite testing negative for celiac disease. This has led to further research and increased publication on the subject. Non-celiac gluten sensitivity continues to be widely debated. Still unclear is whether individuals are reacting to gluten or to some other component in foods. On the other hand, individuals with so-called non-celiac gluten sensitivity actually may have undiagnosed celiac disease.